NASA Photo ID: KSC-72PC-0173
Date taken: 4-16-72

The Apollo 16 Saturn V space vehicle carrying astronauts John W. Young, Thomas K. Mattingly II and Charles M. Duke, Jr., streaks skyward past Florida at the start of NASA's eighth manned voyage to the Moon. Liftoff was recorded at 12:54 p.m. EST April 16, 1972.

Source: http://images.ksc.nasa.gov